40 points bookofjoe 23 hours ago 4 comments

dyauspitr 26 minutes ago | parent

So chronic stress is one of the main contributors to aging. I hope I make it to my 40s.

Do we currently have the ability to do targeted methylation or de methylation at sites in cells?

SlightlyLeftPad 14 minutes ago | parent

Good news! Research shows that hope reduces stress! [0]

[0]: https://www.forbes.com/sites/tracybrower/2024/09/15/how-bein...

dyauspitr 2 minutes ago | parent

What about Xanax or medication. Hypothetically ignoring the ill effects of the drugs themselves will chemical stress relief have the same anti-aging benefits?

Chance-Device 8 minutes ago | parent

I suspect that epigenetic aging is adaptive; a deliberately programmed sequence wherein genes more likely to contribute to age-related mortality are shut down progressively. This being in response to random genetic damage accumulating at a predictable rate.

What we think of as aging then becomes primarily the epigenetic response to the problem of DNA damage, much like the symptoms of a virus are mostly the result of the immune response rather than the virus’s direct effects.